Yang Shi
Office location
87 E Canfield St
Mid-Med Lofts Suite 305
Detroit, MI 48201
Mailing address
Karmanos Cancer Institute
4100 John R.
Mail Code: MM03BI
Detroit, MI 48201
Office phone
(313) 576-8652
Office fax
(313) 576-8656Education training
Education
(2013-2016) Ph.D., Biostatistics, University of Michigan, Ann Arbor, MI
(2011-2013) M.S., Biostatistics, University of Michigan, Ann Arbor, MI
(2009-2011) Graduate Coursework, Biostatistics and Neuroscience, Johns Hopkins University, Baltimore, MD
(2005-2009) B.S., Biological Science, Peking University, Beijing, China
Professional experience
Faculty Appointments
(2024-Present) Assistant Professor, Department of Oncology, Wayne State University School of Medicine, Detroit, MI
(2018-2024) Assistant Professor, Department of Population Health Sciences (primary appointment), Medical College of Georgia, Augusta University, Augusta, GA
(2020-2024) Assistant Professor, Department of Neuroscience and Regenerative Medicine (secondary appointment), Medical College of Georgia, Augusta University, Augusta, GA
(2017-2018) Special-term Associate Professor (not tenured), Department of Epidemiology and Biostatistics, West China School of Public Health, Sichuan University, Chengdu, Sichuan, China
Other Professional Appointments
(2024-Present) Co-Director, Biostatistics and Bioinformatics Core, Karmanos Cancer Institute, Wayne State University, Detroit, MI
(2020-2024) Director, Biostatistics and Bioinformatics Core, Department of Neuroscience and Regenerative Medicine, Medical College of Georgia, Augusta University, Augusta, GA
(2015-2017) Research Scientist, Biostatistics Shared Resource, University of New Mexico Cancer Center, Albuquerque, NM
Major professional societies
American Statistical Association
International Biometrics Society
Honors and awards
(2015) Rackham Conference Travel Fellowship, University of Michigan
(2014) Rackham Conference Travel Fellowship, University of Michigan.
(2013) Public Health Genetics Summer Internship Fellowship, University of Michigan.
(2013) Rackham Centennial Research Fellowship, University of Michigan.
Courses taught
CB8910: Applied Cancer Bioinformatics
CB7700: Recent Developments in Cancer Biology
Research
• Bioinformatics and multi-omics data analysis in cancer research
• Statistical and machine learning approaches with applications in biomedical data analysis
• Computational statistics and Monte Carlo methods with applications in biomedical research
Research interests
Dr. Shi's research interests include bioformatics, analysis of large-scale genomic data and computational statistics. Dr. Shi has a broad range of interests in the application of state-of-the-art statistical methodologies and machine learning algorithms for solving scientific problems in biomedical and public health research, with the aim of elucidating the genetic and molecular mechanism and identifying genetic and environmental risk factors of various types of cancer.
Publications
- Yang Shi, Mengqiao Wang, Weiping Shi, Ji-Hyun Lee, Huining Kang, Hui Jiang (2019). Accurate and efficient estimation of small p-values with the cross-entropy method: applications in genomic data analysis. Bioinformatics, 35 (14): 2441-2448.
- Yang Shi and Ji-Hyun Lee (2018). Sample size calculations for group randomized trials with unequal group sizes through Monte Carlo simulations. Statistical Methods in Medical Research, 27 (9): 2569-2580
- Dali Ding, Weiping Shi, Yang Shi (2018). Numerical simulation of embryo transfer: how the viscosity of transferred medium affects the transport of embryos. Theoretical Biology and Medical Modelling, 15 (1): 20.
- Yang Shi, Arul M Chinnaiyan, Hui Jiang (2015). rSeqNP: A non-parametric approach for detecting differential expression and splicing from RNA-Seq data. Bioinformatics, 31 (13): 2222-2224.
- Kang Wang, Yang Shi, Zhu-Yue Li, Ye-Lei Xiao, Jie Li, Xiang Zhang, Hong-Yuan Li (2019). Metastatic Pattern Discriminates Survival Benefit of Primary Surgery for De Novo Stage IV Breast Cancer: A Real-World Observational Study. European Journal of Surgical Oncology, 45(8):1364-1372.
- Irene Orlow, Yang Shi, Peter A Kanetsky, Nancy Thomas, Li Luo, Sergio Corrales-Guerrero, Anne E Cust, Lidia Sacchetto, Roberto Zanetti, Stefano Rosso, Bruce K Armstrong, Terence Dwyer, Alison Venn, Richard P Gallagher, Stephen B Gruber, Loraine D Marrett, Hoda Anton-Culver, Klaus Busam, Colin B Begg, Marianne Berwick (2018). The interaction between vitamin D receptor polymorphisms and sun exposure around time of diagnosis influences melanoma survival. Pigment Cell & Melanoma Research, 31 (2): 287-296.
- Mei-Fang Xiao, Desheng Xu, Michael T Craig, Kenneth A Pelkey, Chun-Che Chien, Yang Shi, Juhong Zhang, Susan Resnick, Olga Pletnikova, David Salmon, James Brewer, Steven Edland, Jerzy Wegiel, Benjamin Tycko, Alena Savonenko, Roger H Reeves, Juan C Troncoso, Chris J McBain, Douglas Galasko, Paul F Worley (2017). NPTX2 and Cognitive Dysfunction in Alzheimer’s disease. eLife, 6: e23798.
- Jack Cuzick, Orrin Myers, Ji-Hyun Lee, Yang Shi, Julia C Gage, William C Hunt, Michael Robertson, Cosette M Wheeler (2017). Outcomes in women with cytology showing atypical squamous cells of undetermined significance with vs without human papillomavirus testing. JAMA Oncology, 3 (10): 1327-1334.