Cathryn Bock

Cathryn Bock

Cathryn Bock

Position Title

Associate Professor
Population Science

Office Location

Mid-Med Lofts
87 E Canfield
Detroit, MI 48201

Mailing Address

Karmanos Cancer Institute
4100 John R.
Mail Code: MM04EP
Detroit, MI 48201

Office Phone

313-578-4203

Office Fax

313-578-4306

Education Training

Education
(1998-2002)  PhD, Epidemiological Science, University of Michigan, Ann Arbor, MI
(1998-2001)  Trainee, NHGRI Genome Science Training Grant, (PIs: Boehnke, Meisler) University of Michigan, Ann Arbor, MI
(1996-1998)  MPH, Health Behavior & Health Education, Interdepartmental Concentration in Public Health Genetics: School of Public Health, University of Michigan, Ann Arbor, MI
(1984-1988)  B.A.  (magna cum laude), Psychology: Wheaton College, Norton, MA

Postgraduate Training
(2003-2004)  Postdoctoral Research Fellow, Wayne State University and Barbara Ann Karmanos Cancer Institute, Detroit, MI

Professional Experience

Faculty Appointments
(2013-Present)  Associate Professor, Department of Oncology, Wayne State University School of Medicine, Detroit, MI
(2010-2013)  Assistant Professor, Department of Oncology, Wayne State University School of Medicine, Detroit, MI
(2005-2010)  Assistant Professor, Department of Internal Medicine, Wayne State University School of Medicine, Detroit, MI 

Courses taught

FPH 7240: Introduction to Epidemiology

Research Interests

Dr. Bock's primary research interest is focused on explaining the disparately high rates of prostate cancer incidence, aggressiveness, and mortality among African American men in order to inform measures that could reduce these disparities. Her focus is primarily on genetic and environmental risk factors and their interactions. She is currently the PI of a DOD-funded study examining the role of microRNAs in prostate cancer risk, aggressiveness, and PSA relapse in a cohort of African American and European American men recently diagnosed with prostate cancer at the time of study entry. She will be examining both plasma levels of candidate microRNAs as well as genetic variation in genes encoding micrRNAs as well as genes involved in microRNA regulation. She is also interested in admixture mapping as a method for disease susceptibility gene identification, and has completed a prostate cancer admixture mapping project in a sample of African American men. Dr. Bock is also an investigator with the Women's Health initiative, and is involved in several projects, including a gene-environment interaction study of statin use and breast cancer, and another study of micronutrients and kidney cancer. Dr. Bock is affiliated with the Metropolitan Detroit Cancer Surveillance System (MDCSS), a SEER site, and collaborates with investigators using MDCSS and SEER data on a wide variety of research questions. 

Publications

1.                  Powell IJ, Dyson G, Land S, Ruterbusch J, Bock CH, Lenk S, Herawi M, Everson R, Giroux CN, Schwartz AG, Bollig-Fischer A. Genes associated with prostate cancer are differentially expressed in African American and European American men. Cancer Epidemiol Biomarkers Prev. 2013 May;22(5):891-7. Epub 2013 Mar 20. PMID: 23515145

2.                  Bock CH, Powell I, Kittles RA, Hsing AW, Carpten J. Racial disparities in prostate cancer incidence, biochemical recurrence, and mortality. Prostate Cancer, 2011; 2011:716178. Epub 2011 Dec 13. PMID: 22203907 PMCID: PMC3238408

3.                  Schwartz AG, Wenzlaff AS, Bock CH, Ruterbusch JJ, Chen W, Cote ML, Artis A, Van Dyke AL, Land S, Harris CC, Pine S, Spitz M, Amos CI, McKeigue P.  Admixture Mapping of Lung Cancer in 1,812 African Americans Identifies Susceptibility Regions on Chromosomes 1q, 3q and 10q.  Carcinogenesis, 32(3): 312-7, 2011. PMID: 21115650 PMCID: PMC3047238

4.                  Powell IJ, Bock CH, Ruterbusch JJ, Sakr W. Evidence supports a faster growth rate and/or earlier transformation to clinically significant prostate cancer in black than in white American men, and influences racial progression and mortality disparity.  J Urol. May;183(5):1792-6, 2010. PMID: 20299055 

5.                  Bock CH, Schwartz AG, Ruterbusch JJ, Levin AM, Neslund-Dudas C, Land SJ, Wenzlaff AS, Reich D, McKeigue P, Chen W, Heath EI, Powell IJ, Kittles RA, Rybicki BA.  Results from a prostate cancer admixture mapping study in African-American men.  Human Genetics, 126(5): 637-642, 2009. PMID: 19568772

6.                  Patel DA, Bock CH, Schwartz K, Wenzlaff AS, Demers RY, Severson RK.  Sexually Transmitted Diseases and Other Urogenital Conditions as Risk Factors for Prostate Cancer:  A Case-Control Study in Wayne County, Michigan.  Cancer Causes and Control 16: 263-273, 2005. PMID: 15947878

7.                  Bock CH, Peyser PA, Montie JE, Cooney KA.  Decreasing age at prostate cancer diagnosis over successive generations in prostate cancer families.  The Prostate 64: 60-66, 2005. PMID: 15651090

8.                  Bock CH, Wenzlaff AS, Cote ML, Land SJ, Schwartz AG.  NQO1 T allele associated with decreased risk of later age at diagnosis lung cancer among never smokers: results from a population-based study.  Carcinogenesis 26: 381-386, 2005. PMID: 15498787

9.                  Bock CH, Peyser PA, Gruber SB, Bonnell SE, Tedesco KL, Cooney KA.  Prostate cancer early detection practices among men with a family history of disease.  Urology 62: 470-475, 2003. PMID: 12946749

10.              Bock CH, Cunningham JM, McDonnell SK, Schaid DJ, Peterson BJ, Pavlic RJ, Schroeder JJ, Klein J, French AJ, Marks A, Thibodeau SN, Lange EM, Cooney KA.  Analysis of the Prostate Cancer Susceptibility Locus HPC20 in 172 Families Affected by Prostate Cancer. American Journal of Human Genetics 68: 795-802, 2001. PMID: 11179028  PMCID: PMC1274493

PubMed Database Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=cathryn+bock

Faculty Status

Population Science

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