Jessica Back
Position Title
Assistant Professor - Research
Office Location
Karmanos Cancer Institute
Hudson-Webber Cancer Research Center - 615
4100 John R.
Detroit, MI 48201
Mailing Address
Karmanos Cancer Institute
4100 John R., HW06AO
Detroit, MI 48201
Office Phone
313-576-8341
Office Fax
313-576-8356Education Training
Education
(2006) Ph.D., Wayne State University, Detroit, MI
(1998) B.S., Ohio Northern University, Ada, OH
Postgraduate Training
(2006 - 2008) Postdoctoral Fellow, Department of Oncology, Wayne State University, Detroit, MI
Professional Experience
Faculty Appointments
(2022-Present) Assistant Professor - Research, Department of Oncology, Wayne State University School of Medicine ,Detroit, MI
Other Professional Appointments
(2014 - Present) Associate Member, Tumor Biology and Microenvironment Program, Karmanos Cancer Institute, Detroit, MI
(2011 - Present) Associate Director, Microscopy, Imaging, and Cytometry Resources Core, Karmanos Cancer Institute, Detroit, MI
(2018 - 2022) Research Scientist, Department of Oncology, Wayne State University, Detroit, MI
(2010 - 2018) Research Associate, Department of Oncology, Wayne State University, Detroit, MI
(2010) Adjunct Faculty, Oakland Community College, Waterford, MI
Major Professional Societies
International Society for Advancement of Cytometry
Great Lakes International Imaging and Flow Cytometry Association
Board Certification
(2017 - 2023) Specialist in Cytometry, American Society for Clinical Pathology Board Certification.
Publications
Wallace-Povirk A, Rubinsak L, Malysa A, Dzinic SH, O’Connor C, Hou Z, Kim S, Back J, Polin L, Morris RT, Gangjee A, Gibson H, Matherly LH. “Targeted Therapy of Pyrrolo[2,3-d]pyrimidine Antifolates in a Syngeneic Mouse Model of High Grade Serous Ovarian Cancer: Impact on the Tumor Microenvironment.” Sci Rep. 2022 Jul 5;12(1):11346. PMID: 35790779; PMCID: PMC9256750.
Back J, Martinez L, Nettenstrom L, Sheerar D, Thornton S. “Establishing a Biosafety Plan for a Flow Cytometry Shared Resource Laboratory.” Cytometry A. 2022 May;101(5):380-386. PMID: 35037390; PMCID: PMC9081124.
Back JB, Chadick CH, Garcia Vallejo JJ, Orlowski-Oliver E, Patel R, Roe CE, Srivastava J, Walker RV. “Shared Resource Laboratory Operations: Changes Made During Initial Global COVID-19 Lockdown of 2020.” Cytometry A. 2021 Jan;99(1):22-32. PMID: 33175466; PMCID: PMC7898323.
Coku A, McClellan SA, Van Buren E, Back JB, Hazlett LD, Xu S. “The miR-183/96/182 Cluster Regulates the Functions of Corneal Resident Macrophages.” Immunohorizons. 2020 Nov 18;4(11):729-744. PMID: 33208381; PMCID: PMC7891884.
Heyza JR, Lei W, Watza D, Zhang H, Chen W, Back JB, Schwartz AG, Bepler G, and Patrick SM. “Identification and characterization of synthetic viability with ERCC1 deficiency in response to interstrand crosslinks”, Clinical Cancer Research. 2019 Apr 15;25(8):2523-2536. PMID: 30538112; PMCID: PMC6467763.
Patki M, McFall T, Rosati R, Huang Y, Malysa A, Polin L, Fielder A, Wilson MR, Lonardo F, Back J, Li J, Matherly LH, Bepler G, Ratnam M. “Chronic p27Kip1 Induction by Dexamethasone Causes Senescence Phenotype and Permanent Cell Cycle Blockade in Lung Adenocarcinoma Cells Over-expressing Glucocorticoid Receptor”, Scientific Reports. 2018 Oct 30;8(1):16006. PMID: 30375484; PMCID: PMC6207728.
Bernardo MM, Kaplun A, Dzinic SH, Li X, Irish J, Mujagic A, Jakupovic B, Back JB, Van Buren E, Han X, Dean I, Chen YQ, Heath E, Sakr W, and Sheng S. “Maspin Expression in Prostate Tumor Cells Averts Stemness and Stratifies Drug Sensitivity”, Cancer Research. 2015 Sep 15;75(18):3970-9. PMID: 26208903; PMCID: PMC4573892.
Dzinic SH, Chen K, Thakur A, Kaplun A, Bonfil RD, Li X, Liu J, Bernardo MM, Saliganan A, Back JB, Yano H, Schalk DL, Tomaszewski EN, Beydoun AS, Dyson G, Mujagic A, Krass D, Dean I, Mi QS, Heath E, Sakr W, Lum LG, and Sheng S. “Maspin Expression in Prostate Tumor Elicits Host Anti-tumor Immunity”, Oncotarget. 2014 Nov 30;5(22):11225-36. PMID: 25373490; PMCID: PMC4294340.
Bao B, Azmi AS, Aboukameel A, Ahmad A, Bolling-Fischer A, Sethi S, Ali S, Li Y, Kong D, Banerjee S, Back J, and Sarkar FH. “Pancreatic cancer stem-like cells display aggressive behavior mediated via activation of FoxQ1”, Journal of Biological Chemistry. 2014 May 23;289(21):14520-33. PMID: 24719318; PMCID: PMC4031510.
Radkevich-Brown O, Piechocki MP, Back JB, Weise AM, Pilon-Thomas S, and Wei WZ. "Intratumoral DNA electroporation induces anti-tumor immunity and tumor regression", Cancer Immunology Immunotherapy. 2010 Mar;59(3):409-17. PMID: 19730859; PMCID: PMC3702174.
Whittington PJ, Piechocki MP, Heng HH, Jacob JB, Jones RF, Back JB, and Wei WZ. “DNA vaccination controls Her-2+ tumors that are refractory to targeted therapies”, Cancer Research. 2008 Sep 15;68(18):7502-11. PMID: 18794138; PMCID: PMC2562347.